Ogedi-Uzokwe was a member of the youth teams at Leyton Orient, Ilford and Millwall before making the step up to men's football.

His prolific scoring form earned him a contract with English Football League side Colchester United in January 2018.

Following the completion of his loan with Derry, he made a permanent move to Israeli Premier League club Hapoel Hadera in February 2020.

Ogedi-Uzokwe was a member of the youth teams at two English Football League clubs, Leyton Orient and Millwall, separated by a spell at Ilford.

[12] Following a further 14 goalless games for Ogedi-Uzokwe, mostly because he was playing as a midfielder, he scored three goals in April to seal league victories against Çetinkaya Türk and Ci̇hangi̇r.

[21] On 3 January 2018, Ogedi-Uzokwe joined League Two club Colchester United alongside Maldon & Tiptree teammate Ryan Gondoh.

[25] He then scored his first professional goal on his first start for the club from the penalty spot, before turning provider for Mikael Mandron in Colchester's 2–1 win against Coventry City on 13 February.

[30] On 7 February 2019, Ogedi-Uzokwe joined League of Ireland Premier Division side Derry City on loan until 30 June.

[33] His loan was extended to the end of the League of Ireland season after an automatic one-year contract extension was activated by Colchester.

On 5 February, Colchester United announced the departure of Ogedi-Uzokwe to Israeli Premier League side Hapoel Hadera on a permanent contract.

[39] In his 15 appearances and 2 goals in all competitions, Ogedi-Uzokwe helped Sligo to secure a 4th place finish and UEFA Europa Conference League football for the 2021 season.

[41] His competitive debut for the club saw him earn a winners medal as his side won the 2021 President's Cup by beating Shamrock Rovers on penalties after a 1–1 draw at Tallaght Stadium on 12 March 2021.

[42] Ogedi-Uzokwe's first goal for the club came on 17 April 2021 when he scored an 85th minutes equalizer against league leaders St Patrick's Athletic at Oriel Park.

[50] In January 2025, Ogedi-Uzokwe returned to Northern Cyprus for the first time since 2017 to join KTFF Süper Lig side Karşıyaka Anamur.