Constructed for dorector of the Royal Greenland Trade Department Hartvig Marcus Frisch in 1795, some ten years after Kronprinsessegade was established at private initiative by Johan Peter Boye Junge, a master builder and head of Copenhagen Fire Corps, it was shortly thereafter sold to the wealthy widow Cecilie Rosted (née Rohde), who kept it until her death.

A large four-winged building complex surrounding a central courtyard occupied the half of the property that faced the more prominent street Købmagergade.

The half of the property that faced the quieter street Pilestræde was the site of a large garden complex.

[2] In 1783 the property was acquired by the master builder Johan Peter Boye Junge (1735–1807), who was shortly thereafter granted royal permission to establish the new street Kronprinsensgade on the land.

A few years later, Frisch, bought another property in an even more prominent location, on the square Nytorv, opposite Copenhagen's new city hall.

In 1799, Frisch sold the building at the corner of Købmagergade and Kronprinsensgade to the widow Cecilie Margrethe Rosted (née Rohde; 1743–1824).

Her sister Mathilde Catharina Rohde (1838-1790) had married to the wealthy merchant and ship-owner Andreas Bodenhoff.

His death less than half a year later, on 5 June, left the daughter as one of the wealthiest women in the country.

When the daughter also died, just two years later , on 18 July 1798, Cecilie Rosted inherited half of the estate.

Meldal (theology student), three maids (two listed as husjomfru and one as tjenestepige), one male servant, a coachman and a caretaker.

[7] On 30 November 1811, Groth had succeeded Johan Gotlieb Blau as the proprietor of Vajsenhus Pharmacy.

As of 1 June 1812, when Groth was awarded a monopoly on the supply of pharmaceutical products to the army and navy, the official name of his pharmacy was changed to the Royal Military and Vajsenhus Pharmacy (Det Kongelige Militære og Vajsenhus Apotek).

However, as he was only 16 years old when his father died in 1832, the pharmacy was initially run by two trustees, Gjørling and Lund until he was old enough to take over the business, which happened in 1840.

From 1832 to 1834, Albert Heinrich Riise, who would later become a pharmacist and merchant on Saint Thomas in the Danish West Indies, worked at the pharmacy.

nine pharmacists (employees), three apprentices, three maids (two listed as husjomfru and one as stuepige), a female cook and a caretaker.

[10] At the 1850 census, Groth and his wife lived in the building with their now seven children, 12 employees, one male servant and four maids.

On 25 August 1866, Groth sold the pharmacy to the son-in-law and his partner Levin Levinsen Tvede (1834–1880).

[8] On 25 February 1902, Vajsenhus Pharmacy was acquired for DKK 540,000 by Hans Jørgen Vilhelm Trojel (1862–1935).

Back in 1889, Trojel had taken over a materials-and dyes shop (material- og farvehandel) at the corner of Vestergrogade and Saxogade.