The museum is located in the Vacidiye Medrese, a historical medrese (Islamic school) building commissioned by the Germinyanid ruler Umur in 1314.

The building material is cut stone and the portal is of Seljukid style.

The exhibits span the Paleolithic, Chalcolithic, Bronze Age, Hittite, Phrygian, Hellenistic, Roman, Byzantine, Seljukid and Ottoman eras.

The oldest items are painted ceramics from Hacılar.

One interesting item is a sarcophagus of a supposed Amazon, a rare specimen.