Along the way K-148 intersects several major highways including U.S. Route 81 (US-81) east of Norway and US-36 south of Hanover.

The highway travels through mostly rural land and small unincorporated communities, however it does pass through the cities of Agenda and Barnes.

It then passes the unincorporated community of Norway and has an at-grade crossing with a Kyle Railroad track.

The highway then passes by the unincorporated community of Talmo then curves north by Union Cemetery.

It continues north for one mile (1.6 km) then curves back east as it passes along the south side of the unincorporated community of Wayne.

The highway then crosses West Fork Elk Creek then passes along the north edge of Agenda.

[11] As it passes Agenda it crosses Elk Creek then enters into Washington County 2.9 miles (4.7 km) later.

The highway passes by Pleasant Hill Cemetery then intersects Eagle Road, which travels south to Clifton.

The highway continues roughly 4.4 miles (7.1 km) then intersects US-36, which at this point is a four-lane divided freeway.

[15] The highway continues for another .5 miles (0.80 km) then intersects K-243, which heads east to the Hollenberg Pony Express Station.