The KFXF-LD intellectual unit originated on April 20, 1992, when Tanana Valley Television Company signed on K07UU as the area's first commercial station (and fifth in general after KJNP-TV in 1981) since 1955, when KTVF and KATN started.

In its early years, K07UU/KFXF ran programming from Canadian music channel MuchMusic during the overnight hours, and for a time in 1993–94 carried the NBA on NBC.

The station also ran UPN programs from 2000 to 2006, when that network merged with The WB to form The CW, which is shown on a digital subchannel of KATN.

[4] On March 14, 1995, the Federal Communications Commission granted a construction permit for a new low-powered station in Fairbanks,[5] which received the K22EY call letters.

[6] On November 8, 2016, Northern Lights Media, the subsidiary of Gray Television that operates Anchorage stations KTUU-TV and KYES-TV, announced that it would buy KTVF, KFXF-LD and KXDF-CD (then known as KXDD-CD) for $8 million in cash.