All 99 on board died, making the crash the deadliest civil aviation disaster involving a single aircraft at the time, and the deadliest crash involving the Lockheed Constellation series, until the disappearance of Flying Tiger Line Flight 739 in 1962.

[3] All ninety-one passengers and eight crew died in the accident, including six members of the Egyptian fencing team (Osman Abdel Hafeez, Mohamed Ali Riad, Ahmed Sabry, et al.).

Radio contact with the aircraft was lost at approximately 03:40 UTC; a rescue operation was launched which found light debris on the surface of the ocean approximately 180 kilometres (110 mi) northwest of Shannon.

[1] Due to the lack of evidence, Irish and Dutch investigators could not pinpoint a probable cause for the accident.

[5] A memorial to the people who died when KLM Flight 607-E crashed into the sea is located in Bohermore Cemetery, Galway, just inside the main gates.