The three stations share studios on North Market Street and Deer Park Road in northeast Shreveport; KMSS-TV's transmitter is located southeast of Mooringsport.

On May 1, 1987, Media South announced it would sell KMSS-TV to Austin, Texas-based Southwest Multimedia Corp. (owned by Billy Goldberg and Lester Kamin) for $7 million; the sale received FCC approval on June 24.

On April 15, 1993, Southwest Multimedia (under debtor-in-possession entity SWMM-Shreveport Corp.) filed an FCC application seeking to transfer 525 shares in KMSS-TV common stock to Arthur Lanham and Mitchell A.

[8][9] In September 1993, KMSS-TV began maintaining a secondary affiliation with the Prime Time Entertainment Network (PTEN), an ad hoc syndicated programming venture between Chris-Craft Television and Warner Bros.

On March 21, 1994, Southwest Multimedia announced it would sell KMSS-TV to Lafayette-based Associated Broadcasters Inc. (later renamed Communications Corporation of America, and founded by Thomas R. Galloway and D. Wayne Elmore) for $1.5 million; the sale received FCC approval on October 3, 1994.

[10] On June 1, 1995, White Knight Broadcasting—an arm of Associated Broadcasters/ComCorp (owned by media executive Sheldon Galloway), which purchased the station from Word of Life Ministries for $3.8 million that April[11]—entered into a local marketing agreement to operate upstart independent station KWLB (channel 45), which subsequently changed its call letters to KSHV-TV on July 26, under which Associated Broadcasters/KMSS would provide programming, advertising and other administrative services for KSHV.

Channel 45 subsequently migrated its operations from the Word of Life Center on West 70th Street/Meriwether Road (near LA 3132) in southwestern Shreveport into KMSS's Jewella Avenue studios.

During the early- and mid-2000s, KMSS lessened its reliance on running cartoons and classic sitcoms, and began acquiring more talk shows, reality series and court shows, although more recent sitcoms remained as part of its schedule (including as part of its early evening and late prime time lineups surrounding the Fox nighttime schedule).

[16] The sale of ComCorp to Nexstar, as well as that of KMSS to Marshall and a concurring acquisition of the time brokerage agreement with KSHV, received FCC approval on December 4, 2014, and was completed on January 1, 2015.

As a result, Nexstar began operating KMSS and KSHV under separate shared services agreements with Marshall and White Knight, forming a virtual triopoly with KTAL, leaving Shreveport's six major commercial stations under the control of just three broadcasting companies (the Wray family—through Wray Properties Trust—owns KTBS, while KSLA is owned by Gray Television); KMSS and KSHV subsequently migrated their operations into KTAL's North Market Street studios in northeastern Shreveport.

Nexstar issued a statement calling the allegations "spurious and without merit.”[20][21] On December 3, 2019, Marshall Broadcasting Group filed for Chapter 11 bankruptcy protection.

As the SSA partner of KTAL, the station may also simulcast long-form severe weather coverage from the NBC affiliate in the event that a tornado warning is issued for any county (or parish in Louisiana) in its Ark-La-Tex viewing area.

For most of its history, KMSS-TV was one of several Fox-affiliated stations throughout the United States that did not have a local newscast; in lieu of a regular news program, starting in 1991, KMSS ran daily local weather inserts during regular programming that were produced by WeatherVision, a Jackson, Mississippi-based company formed by meteorologist Edward St. Pe to provide weather forecasts for stations without a news department; the agreement with WeatherVision was discontinued in December 2006.

The original format of the broadcast consisted of local news headlines and a local forecast geared specifically towards the program's Ark-La-Tex audience during the first 20 minutes, with the final two segments of the program consisting of a direct partial simulcast of WGMB's live 9 p.m. newscast, which included a national and international news summary from Jeff Beimfohr, along with a statewide sportscast anchored by Chris Mycoskie.