Historically, the station's programming has consisted of several genres of music such as classical and jazz as well as several popular National Public Radio programs such as All Things Considered, A Prairie Home Companion, Car Talk, and Michael Feldman's Whad'Ya Know?
[3] Until 2017, KMST broadcast from studios in the basement of the Curtis Laws Wilson library on the UMR/Missouri S&T campus.
[4] The only local programming retained through the changeover was Wayne Bledsoe's Bluegrass for a Saturday Night, a local staple for many decades,[5] which continued until Bledsoe's August 2017 retirement.
[6] Missouri S&T opted to end KMST's local operations after the University of Missouri system suffered a massive budget cut that led school officials to conclude KMST was no longer part of the school's "academic core.
"[7] KMST was also heard in Lebanon, Missouri via translator K242AN on 96.3 MHz FM, until the translator went silent in August 2020; its license was cancelled by the Federal Communications Commission on March 28, 2022.