[2] In 1718, Kałuszyn was granted town rights by King Augustus II the Strong thanks to efforts of local nobleman Opacki.

[1] Kałuszyn was a private town, owned by several noble families, including the houses of Opacki, Rudziński, Rożniecki and Zamoyski.

Russian anti-Jewish repressions and laws resulted in an influx of Jews (see Pale of Settlement), and in the 19th century, the population was predominantly Jewish.

Russian soldiers surrounded a Polish insurgent unit, but after a short battle the Poles managed to break through the encirclement and escape towards Podlachia.

Economic branches included the manufacture of pottery, flour mills, prayer shawl weaving and the fur trade.

[2] At the beginning of World War II, on 11–12 September 1939, it was the site of the Battle of Kałuszyn between Poles and invading German troops.