The river rises from the eastern Adamawa Plateau, southeast of Garoua-Boulaï (5°53′50″N 14°33′30″E / 5.89722°N 14.55833°E / 5.89722; 14.55833 (Kadéï River headwaters)) in Cameroon's East Province.
The Kadéï is swelled by two tributaries, the Doumé at Mindourou (4°7′45″N 14°34′22″E / 4.12917°N 14.57278°E / 4.12917; 14.57278 (Doumé River mouth)) and the Boumbé (4°6′45″N 15°7′10″E / 4.11250°N 15.11944°E / 4.11250; 15.11944 (Boumbé River mouth)), before flowing east into the Central African Republic.
The Kadéï is part of the Congo River basin.
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