Kaikhosro (also spelled Kay Khusrau, Kai Khusraw; Georgian: ქაიხოსრო) (January 1, 1674 – September 27, 1711), of the House of Bagrationi, was a titular king (a Persian-appointed wali) of Kartli, eastern Georgia, from 1709 to 1711.

Kaikhosro was the son of Prince Levan, and accompanied his father during the service in the Safavid Empire.

Since 1703, Kaikhosro himself served on high posts in the Persian administration, including being a darougha (prefect) of the capital city of Isfahan and a naib (deputy) to the divanbeg (chief justice).

On the death of his uncle, Gurgin Khan (George XI), in 1709, he was confirmed as a wali/king of Kartli and a sipah-salar (commander-in-chief) of the Persian armies in what is now Afghanistan, and granted Tabriz and Barda in possession.

In November 1709, Kaikhosro led a new Persian–Georgian army, supported by contingents from Khorasan, Herat, and Kerman, against the Afghans after Gurgin Khan was assassinated by Mir Wais Hotak, a rebel chieftain of the Ghilzai tribe.