The move took place in the middle of the season and the new Kalamazoo Lassies played their first game, still in their Muskegon uniforms, on June 15, 1950 at Lindstrom Field.

The new Lassies posted their first victory the next night, a 10–2 rout of Rockford led by pitcher Doris Sams and player-manager Bonnie Baker.

In the first round, the team disposed of the South Bend Blue Sox in three games and faced the Fort Wayne Daisies for the Championship Title.

In Game 1 of the AAGPBL Series, Kalamazoo defeated Fort Wayne 17-9 behind a four-hit, seven strong innings from June Peppas, who also helped herself by hitting 2-for-4, including one home run.

Pitching star Maxine Kline, who had posted an 18–7 record with 3.23 ERA for the Daisies during the regular season, gave up 11 runs in six innings and was credited with the loss.