According to John Papa ʻĪʻī, she was betrothed to her half-brother Kamehameha II from birth and they were married when she was twelve and he was seventeen or eighteen.

[3] Her younger sister Kīnaʻu later also became wife of Kamehameha II as did their half-sister Kekauluohi by their mothers Kalakua Kaheiheimalie.

The boat was lined and the whole platform covered with fine imported broadcloth and tapa cloth of rich colors.

)[5] In 1823, Kamehameha II and Kamāmalu left the Sandwich Islands for London, arriving there in May 1824 for a state visit with King George IV.

At first they were buried in a coral house on the grounds of the ʻIolani Palace, but were later moved to the Royal Mausoleum in Nuʻuanu Valley of Oʻahu island.