Kam Woo-sung majored in Oriental painting at the Seoul National University, then made his acting debut in the 1991 television drama Our Paradise.

More characters followed in a variety of genres: a man trapped in a confusing and haunting sequence of events in Song Il-gon's mystery film Spider Forest;[1] the PTSD-afflicted leader of a South Korean squadron in Vietnam who looks into the mysterious disappearance of 18 soldiers in the horror thriller R-Point; and a son struggling to fake Korea's reunification to fulfill an ailing father's wish in the comedy A Bold Family.

[3] He trained extensively over two months in the art of Korean traditional performance, including street opera, and acrobatic, rope and mask dances.

Critics praised Kam's "powerful energy and wit,"[5] and his performance garnered acting recognition, including Best Actor at the 2006 Grand Bell Awards.

[11] Kam was listed as one of the highest paid entertainers on the KBS network in 2011, earning ₩440 million for playing Geunchogo of Baekje in the 60-episode series The King of Legend.