She has been a featured actress in films including Born in East L.A., Deep Cover, The Burning Season, Clear and Present Danger, Lightning Jack, and I Heart Huckabees.

[1] As a filmmaker, her feature film debut, A Single Woman, about the life of first US Congresswoman Jeannette Rankin, won the 2009 Exceptional Merit in Media Award from the National Women's Political Caucus.

[5][6][7] Lopez directed the Spanish-language short film Ese Beso in Madrid, Spain, starring Daniel Freire and Lia Chapman.

[10] In 2009 Lopez created the ERA Education Project, a national media campaign to raise awareness about the Equal Rights Amendment in the United States.

[8] She interviewed women nationwide about how civil rights issues such as equal pay and domestic violence affect their daily lives.