The film tackles how illegal drugs affect the lives of four teenagers.
Kamandag ng Droga was directed by Carlo J. Caparas, an admitted supporter of President Rodrigo Duterte who is known for his campaign against illegal drugs and whose footage was used in the film.
He says that the film is a "cry against drugs whose effect affects the family of those addicted to them, thus bringing a lot of damage to the entire community" and intends the film as medium to remind Filipinos that the illegal drug situation in the country could be resolved through cooperation with authorities and law enforcers.
[3] Francis Joseph Cruz of Rappler, an editorial news website critical of Duterte was critical of Kamandag ng Droga calling it a "grand showcase of lazy filmmaking" and a propaganda.
He added that the film's portrayal of the country's illegal drug problem as simplistic.