Along with his twin brother Kamanawa, Kameʻeiamoku's parents were the keiki aliʻi (prince or child of a chief[1]), Keawepoepoe and Kanoena (w).

As the son of Kalanikauleleiaiwi and Lonoikahaupu, monarch's of several kingdoms between them, Keawepoepoe was an aliʻi (noble) of Hawaii, Maui, Oahu and Kauai.

[7] Fornander also refers to Lonoanahulu, along with the Kameʻeiamoku and Kamanawa in regards to lands passed down to them from Liloa; "Liloa, [king of Hawaii], gave Kekaha in Kona, Hawaii, to Laeanuikekaumanamana in perpetuity, and it descended to his grandchildren through Kualii, Kauluoaonana, Wahulu, Lonoanahulu, etc.

Umi likewise gave Kapalilua, in South Kona, to his child Kapunanahuanui-a-Umi, from whom it descended through Ua, Iwikaualii, lama to Keeaumoku".

[9] Kameʻeiamoku participated in negotiating a treaty in February 1795 with George Vancouver for British support of Kamehameha.

[10] Kameʻeiamoku and his twin Kamanawa were among the four great aliʻi warriors of Kona to support Kamehameha I in his rebellion against his cousin Kīwalaʻō; the other two being their half brother Keʻeaumoku Pāpaʻiahiahi, and Keawe-a-Heulu.

[16] One of his other sons Hoʻolulu would be the father of Kinoʻole o Liliha who married the notable American businessman Benjamin Pitman.

[15] Family tree based on Abraham Fornander's; "An Account of the Polynesian Race" and other works from the author, Queen Liliuokalani's; "Hawaii's Story by Hawaii's Queen", Samuel Mānaiakalani Kamakau's; "Ruling Chiefs of Hawaii" and other works by the author, John Papa ʻĪʻī's; "Fragments of Hawaiian History", Edith Kawelohea McKinzie's; "Hawaiian Genealogies: Extracted from Hawaiian Language Newspapers, Vol.

I & II", Kanalu G. Terry Young's; "Rethinking the Native Hawaiian Past", Charles Ahlo, Jerry Walker, and Rubellite Kawena Johnson's; "Kamehameha's Children Today", The Hawaiian Historical Society Reports, the genealogies of the Hawaiian Royal families in Kingdom of Hawaii probate, the works of Sheldon Dibble and David Malo as well as the Hawaii State Archive genealogy books.