[5] Horn, her mother and her older half-sister Waneek (later a broadcaster and co-captain of the Canadian women's water polo team at the 2000 Sydney Olympics)[6] were notable participants in the 1990 Oka Crisis.

[7] Waneek was stabbed in the chest by a soldier wielding a bayonet while holding Horn, who was then aged four; a photograph of the incident, published on the front page of newspapers, symbolized the standoff between Mohawks and the Canadian government.

[11] Horn's first film acting credit was in 2006 for the CBC television mini-series Indian Summer: The Oka Crisis (for which she had been present at the real-life event sixteen years earlier).

In Web of Lies, a TV movie about a cybersecurity specialist accused of fraud, she played a hacker named Spider.

She appeared in The Wild Hunt, directed by Alexandre Franchi and in Reginald Harkema's Leslie, My Name Is Evil as a member of Charles Manson's death cult.

[13] She starred in the low-budget slasher film A Flesh Offering, directed by Jeremy Torrie, playing an artist who gets lost in the woods.

She starred opposite Famke Janssen, Dougray Scott, Bill Skarsgård, Landon Liboiron and Lili Taylor in the series.

[17] Horn voiced the role of Kaniehtí:io, the Native American protagonist's (Ratohnhake:ton) Mohawk mother, in the 2012 video game Assassin's Creed III, developed by Ubisoft.