[6] Her parents are Arin Thompson and luxury real estate agent William Preston Bowling of Phoenix, Arizona.

Bowling was the first inductee into the Troma Institute For Gifted Youth[11] and listed as one of W Magazine's 42 up-and-comers in their April 2016 "Next in Line" issue.

[14][15] On August 15, 2018, Rolling Stone released a video Bowling directed for the Death Valley Girls' song "Disaster (Is What We're After)".

[20] On October 2, 2018, Stereogum premiered another video Bowling directed for the Death Valley Girls for their song "One Less Thing (Before I Die)".

[24][25] In 2020, Bowling starred as the protagonist, Nancy Banana alongside Bill Weeden in the parody film, Psycho Ape!, and will return for the upcoming sequel.

[29] In early 2020, The Killers debuted a short film to coincide with the release of their new album Imploding the Mirage starring Bowling and Griffin Dunne.

[37] The film stars Cynda McElvana, Brissa Monique, Parker Love Bowling, Caroline Williams, Schooly D, Don Devore, Mickey Madden, Charlotte Kemp Muhl, Charlotte Sartre, Dylan Greenberg, D.C. Douglas, Sune Rose Wagner, and Keith Allison.

[41] The second is titled Prewritten Letters For Your Convenience, which she wrote with her sister, Parker Love Bowling, when they were children and published as adults.