[3] Kansas Wesleyan competes in 25 intercollegiate varsity sports: Men's sports include baseball, basketball, bowling, cross country, football, golf, soccer, tennis, track & field (indoor and outdoor) and volleyball; while women's sports include basketball, bowling, cross country, flag football, golf, soccer, softball, tennis, track & field (indoor and outdoor) and volleyball; and co-ed sports include competitive cheer, competitive dance and eSports.

The Coyotes football program made its first appearance in 1893 with a record of four wins and one loss.

[4] They would not field a team again until 1899 when the school played one game against Kansas State Agriculture College (now known as Kansas State University) and lost by a score of 17–5.

As of completion of the 2009 season, the program has an all-time record of 379 wins, 377 losses, and 38 ties.

[4] Kansas Wesleyan played in American Family Insurance Charity Bowl on December 12, 2000, against rival Bethany.