The station is located at the northern end of the Karşıyaka Çarşı (Main Street).

[1] The station is also a transfer point for minibus services to nearby towns.

The original station was opened on October 10, 1865, by the Smyrna Cassaba Railway.

[2] On June 1, 1934, the Turkish State Railways acquired the station when they bought the SCP.

Karşıyaka station was moved underground and the former trackbed above was converted into a park.