Meḥmed was the eldest son of Karim al-Dīn Ḳarāmān, the soubashi of the region around Ermenek, Mut, Silifke, Gülnar, and Anamur.

Upon Ḳarāmān's death in 1263, Sultan of Rum Kilij Arslan IV arrested his children and brother, emir-i jandar Bunsuz.

When Kilij Arslan died in 1266 and Muʿīn al-Dīn Parwāna assumed full power, the latter released Ḳarāmān's children, except for ʿAlī, who was kept in Kayseri.

Meḥmed further expanded his territory towards the Mediterranean coast and eliminated the Mongol force of 200 men in Ulukışla.

[2] As vizier Mehmet issued his famous firman (decree) ordering the Turkish language to be used instead of Persian and Arabic in government offices.