She is best known for her roles as Kaneesha Carter in the 1989 drama film Lean on Me, Charmaine Brown during the two final seasons on The Cosby Show (1990–1992) and its spin-off A Different World (1992–1993), Nicolette Vandross on Malcolm & Eddie (1996–2000),[1] and as the voice of Dijonay Jones on the Disney Channel animated comedy The Proud Family (2001–2005) and its 2022 Disney+ reboot The Proud Family: Louder and Prouder.

White appeared in recurring guest star roles on Animal Kingdom, Bruh, Better Things, Lodge 49, Kidding, Snowfall, Veep, and I Didn't Do It.

White appeared as a guest star in 9-1-1, The Middle, Mike & Molly, Herman's Head, Hangin' With Mr. Cooper, Roc, My So-Called Life, Chicago Hope, Living Single, The Shield, Southland, How to Get Away With Murder, and Young Sheldon.

[7] In 2022, she reprised her role as Dijonay Jones in the revival series The Proud Family: Louder and Prouder for which she was nominated for an Annie Award for Outstanding Achievement for Voice Acting in a Television Production.

[10] White says that the role provided her an outlet for anger, anxiety, and fear from the COVID-19 pandemic and the social unrest from the deaths of George Floyd and Ahmed Arbery.