Karen S. Lynch (née Rohan, born December 30, 1963) is an American businesswoman and the former president and chief executive officer (CEO) of CVS Health.

[8] Lynch stayed with Magellan until 2012, when she joined Aetna as executive vice president and head of specialty products.

[11] During the COVID-19 pandemic, Lynch took the helm as president and chief executive officer of CVS Health on February 1, 2021, following the retirement of Larry Merlo.

[15] In 2023, Lynch's total compensation from CVS Health was $21.6 million, representing a CEO-to-median worker pay ratio of 392-to-1.

[16] In March 2024, Lynch released a memoir, titled "Taking Up Space: Get Heard, Deliver Results, and Make a Difference".

[18] Lynch was selected for the inaugural 2021 Forbes 50 Over 50, a list of female entrepreneurs, leaders, scientists, and creators over the age of 50.

[23][24] Lynch was honorary co-chair of the Komen Connecticut Race for the Cure benefiting breast cancer research.