Marston earned her Bachelor of Arts from Davidson College in 1990 and her Juris Doctor, magna cum laude, from Wake Forest University School of Law in 1998, where she served as an Articles Editor on the Wake Forest Law Review.

[2] Marston previously served as an Assistant United States Attorney in the United States Attorney's Office for the Western District of North Carolina from 2000 to 2006, receiving the Department of Justice Director's Award in 2002.

She has also served as an adjunct professor at Temple University Beasley School of Law.

President Trump nominated Marston to the seat vacated by Judge Legrome D. Davis, who assumed senior status on September 28, 2017.

[6] On December 18, 2019, the United States Senate invoked cloture on her nomination by a 85–7 vote.