Karimama [ka.ʁi.ma.ma] is a town, arrondissement and commune in the Alibori Department of northeastern Benin.

The commune of Karimana is located 778 kilometres from Cotonou and lies on the Niger River.

Communally it is bounded to the north and east by Niger, south by Malanville and to the west by Banikoara.

Karimana is subdivided into 5 arrondissements; Karimama, Birni-Lafia, Bogo-Bogo, Kompa and Monsey.

The main crops grown are maize, cotton, sorghum, cowpeas, peanut, okra, cassava, onion, potatoes and rice.