It is third largest City in the state and Municipal Corporation and is the headquarters of the Karimnagar district.

The region grew in importance due to its strategic location, contributing to agriculture, trade, and military activities.

In 1937, Janab Shaikhaan Sahab built the Karimnagar Kaman to commemorate the Nizam's Silver Jubilee.

Karimnagar has a population of 397,447 within its corporation limits, according to 2011 census, making it the Third largest city in Telangana state.

[16][17] Karimnagar experiences dry inland climatic conditions with hot summers and cool winters.

Despite the city growing in leaps and bounds, the area of the civic body remaining unaltered.

Karimnagar has evolved into a major health center for its surrounding districts because it is centrally located to all the nearby Districts and Talukas like Jagtial, Siricilla, Ramagundam, Peddapalli, Mancherial, Siddipet, Komaram Bheem, Manthani, Huzurabad, Jammikunta, Husnabad, Sultanabad, Vemulawada, Korutla, Metpalli, Choppadhandi, Manakondur, Bejjanki, Thimmapur, Dharmapuri, Kodimyal, Malyal, Gangadhara and Kalva Srirampur.

The Karimnagar Cable Bridge has been constructed on Manair River between Housing Board Colony and Sadashivpalli, opened in 2023, it shortens the distance to Warangal by 7 KM.

The typical attire includes the traditional Chira and Pancha, and also modern dress styles.

Other major Hindu festivals celebrated in the region include Ugadi, Sri Ramanavami, Vinayaka Chavithi, Holi, Sri Krishna Janmashtami, Dasara, Deepavali, Sankranti, and Maha Sivaratri.

Muslims in this area also celebrate Eid-ul-Fitr, Eid al-Adha, Ramadan (ninth month of the Islamic calendar), Laylat al-Qadr (Shab-e-Qadr), Isra and Mi'raj (Shab-e-Meraj), Shab-e-barat (Mid-Sha'ban), Milad-un-Nabi (Mawlid) and Muharram (Day of Ashura).

[30] Sakinalu a local snack made from rice, gingelly seeds and ajwain during Sankranti festival[31] And Biryani is a common cuisine of the state.

There are many granite quarries on the city outskirts near Baopet, and many Agro based industries, Paddy and cotton are the major crops produced in Karimnagar.

[32] The Lower Manair Dam in Karimnagar has a capacity of 24.5 thousand million cubic feet which can irrigate 4,00,000 acres of land.

Former Information Technology minister of Telangana, KTR laid the foundation stone for an IT hub for the aim of expanding IT to cities like Karimnagar, Warangal, Nizamabad, Khammam and Mahabubnagar.

[33][34] Four integrated markets, a central building to accommodate farmers and grocers wishing to sell their food items, are under construction as of the year 2023.

[39] 72 Electric Vehicle Charging Stations were approved for Karimnagar in 2023 and will operate under the Private Public Partnership model.

[40] Karimnagar railway station provides rail connectivity to the city, located on the Peddapalli–Nizamabad section of New Delhi–Chennai main line.

Karimnagar is connected to cities like Mumbai with a weekly Super fast express, Hyderabad with Kachiguda passenger daily, Tirupati with a biweekly super fast express and Nizamabad with a DEMU train.

[46] The Telugu News publishers in the city are Janam Sakshi, Maithri Channel, Eenadu, ABN Andhra Jyothi.