He pursued a career in administration and became Rentmeister and land judge in Mülheim an der Ruhr.
Starting in 1784, he was active as a saltworks inspector in Gerabronn (near Rothenburg ob der Tauber), which belonged to the margravate of Ansbach at the time.
[2] In 1806, he returned with the aristocratic descriptor von and became (with the help of his older brother Gottlieb, the governor of Dilsberg) full professor in Heidelberg.
The mathematical physics class of the Bavarian Academy of Sciences admitted him to its ranks as a non-local member in 1808.
(He is relative with mathematician Christian Hugo Eduard Study) Langsdorf was also very interested in theological questions and published several works on this topic.