In 1923 he made Schlagende Wetter with Liane Haid and Eugen Klöpfer in the leading roles.
Also that year he made Die Straße ("The Street"), which is considered Grune's most notable film.
He emigrated to England in 1933 and there made Abdul the Damned with Fritz Kortner in 1935, and in 1936 he filmed Ruggiero Leoncavallo's opera Pagliacci with Richard Tauber.
Grune directed the following films in his career:[2] Grune was also a writer for Aus eines Mannes Mädchenjahren, Der Mädchenhirt, Mann über Bord, Die Straße, Die Brüder Schellenberg and Am Rande der Welt.
Das hohe Lied der Liebe (1919) and Wer unter Euch ohne Sünde ist... (1921) with Beate Schach.