Karl Klug (born March 31, 1988) is an American former professional football defensive end who played his entire seven-year career with the Tennessee Titans of the National Football League (NFL).

Klug was selected by the Tennessee Titans in the fifth round of the 2011 NFL draft, 142nd overall.

[3][4] In the 2011 NFL season, Klug led all rookie defensive tackles with 7 sacks, which exceeded initial expectations.

[5] On March 13, 2015, Klug and the Titans agreed to a two-year contract extension.

[6] In 2016, Klug appeared in 14 games with three starts recording 26 tackles, 1.5 sacks, and one pass defensed before suffering a torn Achilles in Week 15 and was placed on injured reserve.