The body is semi-self-supporting with frame and engine with automatic gearbox is placed in the rear part.

The engine drives only the third C axle, meaning that this articulated bus has a pusher configuration.

Prototype of Karosa B941 was built in the year 1995, and is operated until now in Brno, Czech Republic under number 2336.

Between the years 1997 and 2001 was made 335 buses mainly for transport companies in Czech Republic and Slovakia.

Currently, number of Karosa B941/B941E buses is reduced, due to supply of new low-floor buses, for example by SOR NB 18 made in Czech Republic and Iveco Urbanway 18m made in France.