She has been nominated and won several awards for Best Actress including for Premios TVyNovelas and Las Palmas de Oro.

Lozano is a well-known Mexican actress who has appeared in many Televisa telenovelas including Volver a Empezar (1994), Si Dios Me Quita La Vida (1995), Confidente de Secundaria (1996), Pueblo Chico, Infierno Grande (1998), Amar Sin Límites, 1999–2000 series Tres mujeres,[2] El Manantial, Niña amada mía (which aired on Univision simultaneously) and the Venevisión telenovela Soñar no Cuesta Nada, entirely shot in Miami, Florida.

Lozano has also participated in theater in plays such as Anastasia, Cinderella and Grease, with the role of Sonia.

In 2004 she played the lead role in the film Desnudos, an artist physically and mentally abused by her boyfriend, a performance that earned her a nomination for an Ariel Award.

In 2010 Lozano made her debut on U.S. movie screens with For Greater Glory (Cristiada) alongside Eva Longoria and Andy Garcia.