[3] They can be found in many types of habitats, such as shrublands, grasslands, and wetlands, at elevations as high as 2,000 metres (1.2 mi).

[8] Males are a little smaller than females, and they have chocolate-coloured vocal sacs that can grow nearly twice their normal size during calls.

[4] Identification of tadpoles can be difficult, as there is much variation among them, a trait shared with other species in the genus Kassina.

In the northern parts of its distribution, specifically Kenya and Tanzania, the relationship between its range and that of its relative Kassina somalica is not well understood.

It is found in many different habitats, including savannas (both humid and dry), montane grasslands and shrublands, wetlands, and artificial environments (such as pastures and canals).

[5] Senegal running frogs secrete the peptide Kassinakinin S from their skin, which induces the release of histamine from mast cells.

Potential predators that consume this peptide experience painful inflammation that allows other secretory products to enter their bloodstream.

[6] The International Union for the Conservation of Nature (IUCN) has rated K. senegalensis as a least-concern species, citing its extensive range and tolerance of many different habitats.

It is unclear whether this species' large estimated population has significantly changed in recent years.

On a local scale, Senegal running frogs may be affected by particularly severe habitat degradation.