[2] Cross has played domestic cricket for a number of teams including Lancashire, North West Thunder, Northern Superchargers and Royal Challengers Bangalore.

In January 2010 she was called up to join the 2010/11 England Women tour of Australia after injuries to Beth Morgan and Claire Taylor.

[9][10] In February 2019, she was awarded a full central contract by the England and Wales Cricket Board (ECB) for 2019.

[11][12] In June 2019, the ECB named her in England's squad for their opening match against Australia to contest the Women's Ashes.

[15] On 18 June 2020, Cross was named in a squad of 24 players to begin training ahead of international women's fixtures starting in England following the COVID-19 pandemic in the United Kingdom.

[16][17] In December 2020, Cross was announced as one of the commentators to feature on Talksport's commentary for England men's 2nd ODI against South Africa.

[25] In December 2021, Cross was named in England's squad for their tour to Australia to contest the Women's Ashes.

[30] Cross captained England for the first time in an ODI against Ireland at Stormont in Belfast on 7 September 2024, marking the occasion by taking career best bowling figures of 6/30 and scoring 38 not out with the bat to lead her team to a four-wicket victory in the first contest of a three-match series.

[35][36] Cross's father David was a professional footballer between 1969 and 1987, most notably for West Ham United, where he won the FA Cup in 1980.