She was nominated for a Tony Award for her performance as Lady Macbeth in Macbeth, at Chichester Festival Theatre and the West End and Broadway and an Olivier Award nomination in 2012 for her performance as Julie in London Road at the National Theatre.

Her film and television credits include Vanity Fair (2004), Harry Potter and the Deathly Hallows – Part 1 (2010), Macbeth (2010), Philomena (2013), London Road (2015), Harlots (2017–2019), and The Wheel of Time (2021).

Fleetwood grew up on a farm in Arden, Warwickshire near Stratford-upon-Avon,[1] and she is a graduate of Exeter University.

[1] In 2008, Fleetwood was nominated for a Tony Award for her performance as Lady Macbeth in Macbeth, opposite Patrick Stewart, which first opened at Chichester Festival Theatre and was transferred to the West End and Broadway,[3] In 2012, she was nominated for the Laurence Olivier Award for Best Actress in a Musical, for her performance as Julie in London Road at the National Theatre.

[6] She is married to Rupert Goold,[1] who directed her in Macbeth;[7] they have a son and a daughter.