She works in theatre, television and film, with roles in Hunters (2020–2023), The Great Gatsby (2013), Griff the Invisible (2010) and The Final Winter (2007).
[6] Mulvany was diagnosed with a Wilms's tumor (renal cancer) at age two and spent much of her childhood in hospital.
Her cancer may be linked to her father's exposure to Agent Orange (dioxin) during his service in the Vietnam War, although this has not been proven.
[9] She played Cassius,[10] Lady Macbeth, and was lauded for her performance as Richard III in which she revealed her real-life spinal disability.
[16] In 2018, Mulvany adapted Ruth Park's The Harp in the South trilogy as a two-part play for Sydney Theatre Company.
[19] One review said, "Mulvany’s bold adaptation recentres the queens, shearing away nearly every male soliloquy and interaction held exclusively between men, of which there are an abundance in Schiller’s text",[20] while others called it "dazzlingly different",[18] and a "feminist"[21] reimagining of a classic.