Katherine married secondly Piers or Peter Edgcumbe (died August 1539) of Cotehele in Cornwall, by 1525, when in 1524–5, Sir Piers and Katherine were sent three gallons of wine “at their first homecoming.”[2] A carved panel from a bed tester still at Cotehele, depicting the Expulsion of Adam and Eve, is sometimes said to have been hers.
[6] The three women made and signed a formal deposition or statement about this conversation,[7] which was relevant to the issue of whether the royal marriage had been consummated.
In July 1543 Henry VIII wanted English servants to join the household of the infant Mary, Queen of Scots, who he hoped would marry his son Prince Edward.
Sadler wrote that his own wife, Ellen Mitchell, who was pregnant, was not suitable because she was unused to life at court, and an older woman and experienced courtier like Lady Edgcumbe would be better:And, in my poor opinion, it were the more necessary, that she, whom your majesty would have to be resident about the young queen's person here, were a grave and discreet woman, of good years and experience; and the better if she were a widow, as I think the lady Edongcomb were a meet woman for such purpose, and many others, whereof I doubt not your majesty hath choice enough[11]Katherine Edgcumbe did not go to Scotland, as the marriage plans negotiated by Henry VIII as the Treaty of Greenwich came to nothing, and instead he launched the war now known as the Rough Wooing.
She left household goods, some of which had belonged to Griffith ap Rhys, to her daughter Mary Luttrell at Dunster Castle.