She has held roles in leadership, engineering, product management, and data science at Google, IBM, the Georgia Tech Research Institute, Harris Healthcare,[1][2][3] and served as a founding product and engineering member of the United States Digital Service (USDS) in the Executive Office of the President of the United States at The White House.

Pham was the Deputy Chief Technology Officer for Product and Engineering at the Federal Trade Commission,[4] and the inaugural Executive Director of the National AI Advisory Committee.

[11] Pham has been part of a championship StarCraft II team,[12] and placed 1st the Imagine Cup competition, representing the United States with a sentiment analysis (EmotionAI) engine.

Her brother, United States Marine Corps Major David Pham, was presented the Purple Heart medal during combat operations in Afghanistan.

[18] While in university, Pham was the chair of Georgia Tech's Women in Computing,[19] director of technology at Phi Mu fraternity, researcher in the Bio-Medical Informatics and Bio-Imaging Lab,[20] and founded the southeast chapter of United for Sight.

[27]Since 2017, Pham has been selected as a Fellow, and now Affiliate, at Harvard University’s Berkman Klein Center for Internet and Society, where her research spans technology, policy, healthcare, artificial intelligence, and the social responsibility and ethics of the tech industry.

[40] Pham has served as an advisory board member of the Anita Borg Institute[41] and the Make the Breast Pump Not Suck Initiative.