Born in East Berlin, German Democratic Republic, Lompscher grew up in a three child household.

After giving birth to her son, she worked as a research assistant at the Institute of Urban Design and Architecture at the Bauakademie in Berlin.

While in the body, Lompscher served as Deputy Leader of Die Linke’s parliamentary group and as its spokesperson for Urban Development, Building and Housing.

On 31 January 2017 she resigned from the Abgeordnetenhaus and was replaced by fellow party member Philipp Bertram.

Lompscher, a self-described “pleasure smoker”, is an advocate for non-smoker protection, but has spoken out against what she calls a “militant smoking ban”.