Kaukauna (/kəˈkɔːnə/ ⓘ) is a city in Outagamie and Calumet counties, Wisconsin, United States.

It is situated on the Fox River, approximately 100 miles (160 km) north of Milwaukee.

Claude Allouez, commented on the "apple trees and vine stalks in abundance" that he found the people of Kaukauna cultivating.

Kaukauna became an outpost of trade in Green Bay and saw much intermarriage between French and Menominee people, leading to a Métis culture which produced local leaders such as Augustin Grignon.

He obtained 1,281 acres (518 ha) from the Menominee Indians for two barrels of rum and other gifts.

The property was purchased by Charles A. Grignon (and recorded Dec. 18, 1828), who built a mansion on the river on Kaukauna's north side.

The home, which bears Grignon's name, is operated as a museum by the Outagamie County Historical Society.

[8] In 1836, following years of negotiations about how to accommodate the Oneida, Stockbridge-Munsee, and Brothertown peoples who were removed from New York, the Menominee ceded over four million acres of land to the United States in the Treaty of the Cedars.

[citation needed] US 10 is just to the south of Kaukauna, and Wisconsin Highway 441 is just to the west.

The city has diverse industrial and manufacturing businesses, including the Oscar Thilmany Paper Mill, constructed in 1883.

The name dropped off the mill when it was purchased by HammerMill in 1969, which was in turn bought by International Paper in 1986.

It is now owned by KPS Capital Partners, and was renamed Expera Specialty Solutions in 2013.

Kaukauna cheese, once made in the city, is now manufactured by the Bel/Kaukauna corporation in the neighboring village of Little Chute.