After Ryazan, the south-eastern line branches a number of times, so that trains originating from Kazansky station serve most of south-eastern Russia, Kazakhstan, and the post-Soviet Central Asian states (mostly via the Trans-Aral line).

Occasionally, long-distance trains serving the eastbound Moscow-Nizhny Novgorod line use Kazansky station as well.

However, the commuter trains of that line never do so, as they always arrive to Moscow's Kursky Rail Terminal.

[2] Construction of the modern building according to the design by architect Alexey Shchusev started in 1913 and ended in 1940.

Suburban commuter trains (elektrichka) connect Kazansky station with the towns of Lyubertsy, Zhukovsky, Gzhel, Kurovskoye, Shatura, Cherusti, Vekovka, Bykovo, Ramenskoye, Bronnitsy, Voskresensk, Yegoryevsk, Kolomna and Ryazan.