She is mostly known for playing Lane Kim in Gilmore Girls and NYPD medical examiner Dr. Edrisa Tanaka on FOX's crime drama Prodigal Son (2019–2021).

She attended Mid-Pacific Institute preparatory school in Oʻahu, and Whitman College for one year as a drama major.

Agena married Shin Kawasaki in a helicopter over Las Vegas Valley, Nevada, on December 19, 2005.

Agena rides motorcycles, she arrives at the Warner Brothers studio lot on a Yellow 1970s Kawasaki Ninja 250.

Agena also appeared in three episodes of Felicity as Leila Foster, a girl who comes to the lead character for assistance in acquiring the morning-after pill and participates in a protest when denied the medication.