It serves the western suburb of St Albans, in Melbourne, Victoria, Australia.

[4] Keilor Plains station opened on 27 January 2002, as part of the extension of the electrified network from St Albans to Sydenham.

[4] In 1986, boom barriers were installed at the former Taylors Road level crossing, which was located at the down end of the station.

[6] In April 2007, construction commenced on a grade separation project, which involved lowering the road underneath the railway line.

CDC Melbourne operates two routes via Keilor Plains station, under contract to Public Transport Victoria: