[3][4] After red-shirting his first year at Stanford in 2014, Chryst appeared in four games as a backup to Kevin Hogan.

[6] Chryst made his debut as the starting quarterback on October 29, throwing for 104 yards and two touchdowns against Arizona.

[8] The next week, he threw two touchdowns and 198 yards as well as running for another score in a 45–31 win over California at the 119th annual Big Game.

[11] In his five starts in the regular season, Chryst went 5–0, throwing nine touchdowns and only one interception, including 774 passing yards.

[12] At the 2016 Sun Bowl, Chryst threw a touchdown and left in the second quarter with a knee injury in a 25–23 win over North Carolina.

[16] The following week, Chryst led a fourth quarter game-winning drive against Oregon State in Corvallis.

He completed a pass to J.J. Arcega-Whiteside on a fade route with 20 seconds left to win the game.