Following the disbanding of Destiny's Child in 2006, Rowland released her second studio album, Ms. Kelly (2007), which produced the international top-ten hits "Like This" (featuring Eve) and "Work".

Rowland has also received a star on the Hollywood Walk of Fame as part of Destiny's Child, and as a solo artist, she has been honored by the American Society of Composers, Authors and Publishers and Essence for her contributions to music.

[31] That same year, Luckett and Roberson withdrew their case against their now-former bandmates, while maintaining the suit against Mathew, which ended in both sides agreeing to stop public disparaging.

[45] Released to an even bigger success in international territories, Simply Deep topped the UK Albums Chart and became a gold-seller in Australia,[47] Canada,[48] and New Zealand,[49] resulting in worldwide sales total of 2.5 million copies.

[51] She continued her acting career the following year, with guest roles in UPN sitcom Eve as Cleo, and in NBC drama series American Dreams as Martha Reeves.

[52] In August 2003, Rowland made her big-screen debut playing the supporting role of Kia Waterson alongside Robert Englund and Monica Keena in the slasher film, Freddy vs. Jason, which grossed $114.5 million at the box office worldwide.

[60] After Hurricane Katrina in 2005, Rowland and Beyoncé founded the Survivor Foundation, a charitable entity set up to provide transitional housing for victims and storm evacuees in the Houston, Texas area.

Rowland initially hoped her three-episode stint would expand to a larger recurring role, but as the show was moved to The CW Television Network the following year, plans for a return eventually went nowhere.

"[63][64] Rowland eventually consulted additional producers to collaborate on the album, including Billy Mann, Mysto & Pizzi, Sean Garrett, Scott Storch, and Polow da Don.

[66] Outside the US, the album widely failed to reprise the success of Simply Deep, barely reaching the top-forty on the majority of all charts it appeared on, except for the UK, where it opened at number 37.

The previously unreleased Bobby Womack cover "Daylight", a collaboration with Travie McCoy, served as the EP's lead single and was a moderate success in the UK.

[67] In 2007, Rowland, along with stars such as Jessica Simpson and the cast of Grey's Anatomy autographed pink Goody Ouchless brushes that were made available for auction on eBay, with all proceeds going to Breast Cancer Awareness.

[72] Two months later, Rowland appeared as a choirmaster in the first season of the NBC talent show Clash of the Choirs among other musicians such as Michael Bolton, Patti LaBelle, Nick Lachey, and Blake Shelton.

[76] That same year, she spearheaded a bone marrow drive,[77] and joined fellow singers Alesha Dixon and Pixie Lott to create T-shirts for River Island in aid of the Prince's Trust, profits from which help change young lives.

[82] In April 2009, Rowland was featured on David Guetta's single "When Love Takes Over", which topped many charts in Europe, selling over 5,5 million copies worldwide,[83][84][85] and received a Grammy Award nomination for Best Dance Recording.

[90] In 2010, Kelly Rowland launched I Heart My Girlfriends, a charity that focuses on self-esteem, date violence prevention, community service, abstinence, sports, drug/alcohol/smoking avoidance, obesity, disabilities, and education.

It also included another successful single "Motivation", with Lil Wayne, which topped the R&B/Hip-Hop Songs chart for seven consecutive weeks and was certified double platinum by the Recording Industry Association of America (RIAA).

[112] In April 2012, Rowland toured Australia alongside Ludacris, Chris Brown, Trey Songz, T-Pain, Ice Cube, Lupe Fiasco, and Big Sean for the urban festival, Supafest.

[114] The film, which also starred Michael Ealy, Jerry Ferrara, Meagan Good, Regina Hall, and Kevin Hart, topped the US box office and grossed $91.5 million.

[128] During an interview with HuffPost Live on March 26, 2014, Rowland revealed that she has begun recording her fifth studio album and said the new music, which encompasses horns, drums, and flutes, was influenced by iconic female singers including Diana Ross.

Rowland, along with Missy Elliott, Kelly Clarkson, Zendaya, Janelle Monáe, Lea Michele, and Chloe x Halle were all featured on a charity single put together by US First Lady Michelle Obama.

[168] In November 2021, Rowland released a cover of "Wonderful Time" to support her third holiday movie, Merry Liddle Christmas Baby, which aired that month on Lifetime.

"[202] Other inspirations include: Martin Luther King Jr.;[202] Mariah Carey;[203] Mary J. Blige;[204] Naomi Campbell;[205] and Oprah Winfrey, whom she describes as "the female version of God.

[218] The following year, Rowland returned to the big screen, this time for a lead role in the romantic comedy The Seat Filler, starring opposite Duane Martin and Shemar Moore.

[109][223][224] In addition to her judging stint, Rowland also had a supporting role in the motion picture Think Like a Man (2012), which also starred Keri Hilson, Chris Brown and Gabrielle Union.

[120] Rowland and the Knowles family founded the Survivor Foundation, a charitable entity set up to provide transitional housing for 2005 Hurricane Katrina victims and storm evacuees in the Houston, Texas, area.

[71] In 2007, Rowland, along with stars such as Jessica Simpson and the cast of Grey's Anatomy autographed pink Goody Ouchless brushes that were made available for auction on eBay, with all proceeds going to Breast Cancer Awareness.

[234] Also, in 2009, Rowland, along with fellow singers Alesha Dixon and Pixie Lott, created T-shirts for River Island in aid of The Prince's Trust, profits from which help change young lives.

According to Rowland's official website, the charity focuses on self-esteem, date violence prevention, community service, abstinence, sports, drug and alcohol and smoking avoidance, obesity, disabilities, education, and more.

With "Dilemma", Rowland became the first Destiny's Child member to achieve a Billboard Hot 100 and a worldwide number-one single, and to win a Grammy Award as a solo artist.