Kelso is a village in Scott County, Missouri, United States.

U.S. Route 61, often called the Blues Highway, passes through Kelso.

[6] According to the United States Census Bureau, the village has a total area of 0.32 square miles (0.83 km2), all land.

There were 243 housing units at an average density of 759.4 per square mile (293.2/km2).

22.4% of all households were made up of individuals, and 10.1% had someone living alone who was 65 years of age or older.

There were 226 housing units at an average density of 709.0 per square mile (273.7/km2).

28.2% of all households were made up of individuals, and 17.1% had someone living alone who was 65 years of age or older.