Hyped professionally as "The Meanest Man in the Movies," the vast majority of his over 250 appearances on camera were Westerns, but he also did occasional forays into horror, crime drama, and science fiction.

Duncan's final appearances on screen were Wood's low-budget The Sinister Urge, and a bit part in an episode of Rawhide ("Incident of the Sharpshooter").

He also made television appearances, especially westerns, such as The Cisco Kid, Bat Masterson, The Life and Legend of Wyatt Earp, and Tombstone Territory.

"[3] Makeup man Harry Thomas saw Kenne Duncan naked at a Hollywood party once, and remarked years later to an interviewer "You know, all men are not created equal.

Ed Wood was named executor of Kenne Duncan's estate, and he held a small memorial funeral in his backyard around the swimming pool.