Kennedy Mweene (born 11 December 1984) is a retired Zambian professional footballer who played as a goalkeeper.

On club level he spent most of his career in South African Premier Soccer League clubs Free State Stars and Mamelodi Sundowns.

Renowned for his penalty-saving and penalty-taking skills, Mweene was arguably one of the best goalkeepers in Africa, winning the PSL Goalkeeper of the Season award (best player in the South African top division) in the 2008–09 season.

He played for Free State Stars until the end of the 2012–13 season.

On 12 February 2012, Mweene kept a clean sheet during the 2012 Africa Cup of Nations Final and saved one penalty kick (as well as successfully converted his own) in the shootout to decide the game, which was eventually won by Zambia.