US 421 near Eminence US 127 in Owenton I-75 in Dry Ridge US 25 in Dry Ridge US 25 in Williamstown Kentucky Route 22 (KY 22) is a 121.213-mile-long (195.073 km) east–west highway running from the eastern suburbs of Louisville to an unincorporated place called Willow in Bracken County in Northern Kentucky.

It begins at US 42 at the city limit of a Louisville suburb called Northfield, Kentucky, and carries the name Brownsboro Road, a local road which begins near Downtown Louisville.

The highway runs 0.336 miles (0.541 km) between junctions with KY 22 and US 25 Business, passing through the heart of Dry Ridge.

It was formed in 2005 with the opening of the Dry Ridge Bypass, which rerouted KY 22 around the city.

[2] The entire route is in Dry Ridge, Grant County.