The highway crosses over Logtown Road and intersects EastPark Drive, which serves the south unit of the eponymous business park.
The highway intersects Technology Drive, which serves the north unit of the business park, including a campus of Ashland Community and Technical College.
The highway descends into the valley of the East Fork of the Little Sandy River and has a four-ramp partial cloverleaf interchange with KY 207 (Argillite Road).
At the bottom of the hill, the highway intersects US 23 immediately before reaching its northern terminus at KY 3105 (Wurtland Avenue).
The northern terminus junctions US 23 at a traffic signal and actually continues northward .1 of a mile north to KY 3105 (old US 23).
Since being completed, the Industrial Parkway has saved over 30 minutes of travel between Greenup and Grayson on the curvy and dangerous KY 1.